Vinnies Next Space Adventure Game
Welcome to VSNAG (Needs a better name, Stat 8-)!
Aliens, both critters and starfarers, and their worlds. This is going to be a wide-ranging but hard SF setting, so I need to decide on exactly what the scope is- A galactic arm or a few star systems?
After that, take a look at your wiki. There is some more helpful info there.